KNOWLEDGE-BASED VIDEOS

Enhancing Your Assay Familiarity for Drug Discovery & Development

Knowledge-based, on-demand videos are short video recordings for drug discovery and development scientists covering a variety of topics about Eurofins DiscoverX products, technologies, and capabilities to help you accelerate your drug discovery and development programs with confidence.

Immuno-Oncology

► Novel Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Learn about PathHunter® checkpoint receptor assays (cell lines and bioassays) for innate and adaptive immunity. 

Assays discussed include functional cell-based assays for immunoglobulin and TNFR superfamilies like CD28, ICOS, PD1, CD47, SIRPα, and OX40 and assays for testing agonist antibodies (clustering and binding assays for bi-specifics). 28 min.

View Related Products discoverx.com/checkpoint

► KILR Platform for Cytotoxicity Applications
Learn how KILR® cytotoxicity assays eliminates these issues with a simple, non-radioactive and dye-free method to specifically measure target cell death in a co-culture with effector cells.

Assays for cancer immunotherapy drugs need to detect target cancer cell death when co-cultured with immune effector cells. Radioactive or leaky dyes make it difficult to specifically detect target cell death in a co-culture with immune effector cells. 25 min.

View Related Products discoverx.com/KILR

► Single Donor-Derived KILR CD16 Effector Cells for ADCC and T Cell Redirection Applications
Learn how KILR® CD16 effector cells ensure assay reproducibility with higher signal to background ratios, without worrying about donor variability.

PBMC effector cells have inherent donor variability, reducing their consistency and reproducibility in lot release assays. Antibody-Dependent Cell Cytotoxicity (ADCC) assays that measure cell death often have low signal to background ratios and suffer from this donor variability of the PBMCs. 28 min.

View Related Products discoverx.com/KILR

Bioassays

Bioassays and Cell Banking Program topics Coming Soon

Small Molecules

Compound-Target Engagement and Protein Turnover Assay topics Coming Soon

Target Focused

GPCRs, Cytokines/Interleukins, RTKs, and Signaling Reporter Assay topics Coming Soon

Translocation

Pharmacotrafficking and Cellular Translocation Assays topics Coming Soon

Toolbox

Do-it-Yourself Assays topic Coming Soon

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