► Pharmacotrafficking Assays
Learn about PathHunter® pharmacotrafficking assays to identify small molecule compounds that rescue disease relevant mutant membrane proteins like GPCRs, ion channels, and transporters.
Discover how these quantitative, antibody- and image-free cell-based assays can be used to screen compounds (called pharmacological chaperones) that stabilize mutated membrane proteins allowing for their proper trafficking to the cell membrane. Applications discussed include rescuing conditions like retinitis pigmentosa, obesity, diabetes, cystic fibrosis, and
cardiac arrhythmias. 30 min.
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