Learn What Makes Allosteric Molecules So Special

Download this white paper to learn more about how you can utilize GPCR allosteric modulation to expand your drug discovery:

  • Allosterism can change the very nature of receptors, including their efficacy and functional signaling

  • Allosteric molecules binding to separate sites on the receptor allows them to modulate or potentiate receptor effects, essentially re-setting physiology

  • Allosteric effects are probe dependent, allowing precise discrimination between endogenous molecules and signaling proteins